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The authors established FOXO4-DRI as a first-in-class senolytic peptide tool for cellular senescence research, with mechanistic selectivity grounded in the elevated FOXO4-p53 interaction in senescent versus non-senescent cells

The Therapeutic Guidelines: Oral and Dental Version 4 reinforces this in its section, "Guidance for medical practitioners managing oral and dental issues", which underscores the importance of addressing the unique requirements of pregnant patients [3]

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Understanding how collagen production declines and taking steps to protect and support collagen, such as using sunscreen, eating a nutrient-rich diet, and incorporating collagen-boosting skincare ingredients, can help us slow the aging process and maintain healthier, more youthful-looking skin

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Each patient should undergo individualized risk assessment before treatment initiation